Key result
Microvascular brain damage, driven by aging and hypertension, is a potent risk factor for cognitive decline, though evidence that antihypertensive treatment prevents dementia remains lacking.
Why the study?
Does cardiovascular risk factor control prevent cognitive decline and dementia in older individuals with hypertension?
Does cardiovascular risk factor control prevent cognitive decline and dementia in older individuals with hypertension?
Further specifically designed clinical trials are needed to demonstrate whether antihypertensive treatment can limit microvascular brain damage and reduce the risk of dementia.
No takes yet. Share an insight, caveat, or question.
Antihypertensives should not yet target dementia prevention; leaves open whether they limit microvascular damage in dedicated trials.
Scuteri et al. (2011) conducted a review in Microvascular brain damage, aging, and hypertension. Aging and hypertension was evaluated. Microvascular brain damage, driven by aging and hypertension, is a potent risk factor for cognitive decline, though evidence that antihypertensive treatment prevents dementia remains lacking.
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