June 1, 1975HeartOpen Access

Phentolamine for vasodilator therapy in left ventricular failure complicating acute myocardial infarction. Haemodynamic study.

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Why the study?

Does intravenous phentolamine improve haemodynamic parameters in patients with left ventricular failure complicating acute myocardial infarction?

Population

15 patients with acute myocardial infarction associated with signs of left ventricular dysfunction

Design

Case_series

Authors

CPC l PerretUniversity of Lausanne JGJ. P. GardazUniversity Hospital of Lausanne MRMarc ReynaertCliniques Universitaires Saint-Luc

Discussion

Member takes

Implication

May support phentolamine for acute hemodynamic stabilization post-MI LV failure; hypothesis-generating case report requiring randomized confirmation.

Structured PICO

Does intravenous phentolamine improve haemodynamic parameters in patients with left ventricular failure complicating acute myocardial infarction?

Population

15 patients with acute myocardial infarction associated with signs of left ventricular dysfunction

Intervention

Phentolamine infused intravenously at a dose of 10 mg per hour

Outcome

Changes in haemodynamic parameters including right atrial pressure, pulmonary capillary wedge pressure, cardiac index, vascular resistances, and mean arterial pressuresurrogate

Intravenous phentolamine improves hemodynamics by reducing preload and afterload in patients with left ventricular failure complicating acute myocardial infarction.

Cite This Study

Perret et al. (1975) studied this question.

synapsesocial.com/papers/6a71d0c3c2d7c30908271fa4 https://doi.org/10.1136/hrt.37.6.640

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Implication

May support phentolamine for acute hemodynamic stabilization post-MI LV failure; hypothesis-generating case report requiring randomized confirmation.

Phentolamine for vasodilator therapy in left ventricular failure complicating acute myocardial infarction. Haemodynamic study.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Phentolamine for vasodilator therapy in left ventricular failure complicating acute myocardial infarction. Haemodynamic study.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider