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February 25, 2015BMC Cardiovascular DisordersOpen Access

A case report of eosinophilic myocarditis and a review of the relevant literature

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Key result

High-dose corticosteroid therapy successfully reversed severe cardiac injury and restored cardiac function in a patient with eosinophilic myocarditis caused by antituberculosis drugs.

Population

n=1, 43-year-old Chinese male with a 5-year history of hypertension, presenting with eosinophilic…

Design

Case_report

Authors

HLHaiying LiZDZhenyu DaiBWBinqiao Wang

Discussion

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Overview

May support corticosteroids in antituberculosis-induced eosinophilic myocarditis; hypothesis-generating and requires prospective validation.

Study Design

Type

Case Report (n=1)

Multicenter

No

Structured PICO

P
Population
A 43-year-old male who developed severe eosinophilic myocarditis secondary to antituberculosis drugs and was treated with high-dose corticosteroids.
I
Intervention
Methylprednisolone pulse therapy (80 mg, then 500 mg daily for 3 days, then 60 mg for 7 days, tapered to 5 mg every two weeks).
O
Outcome
Reversal of cardiac injury and recovery of cardiac function

High-dose corticosteroids can effectively reverse cardiac injury and improve prognosis in patients with eosinophilic myocarditis secondary to antituberculosis drugs.

Limitations

  • Difficulties in establishing the diagnosis of eosinophilic myocarditis
  • Current non-invasive techniques provide limited ability to establish a definitive diagnosis
  • Endomyocardial biopsy has limited sensitivity and specificity

Cite This Study

Li et al. (2015) conducted a case report in Eosinophilic myocarditis (n=1). High-dose corticosteroids (methylprednisolone) was evaluated on Clinical recovery and cardiac function. High-dose corticosteroid therapy successfully reversed severe cardiac injury and restored cardiac function in a patient with eosinophilic myocarditis caused by antituberculosis drugs.

synapsesocial.com/papers/6a71d3d835aa2c282ce2f27bhttps://doi.org/10.1186/s12872-015-0003-7
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Also Consider

Synapse has enriched one closely related paper. Consider it for comparative context:

  1. 1Eosinophilic myocarditis associated with dense deposits of eosinophil cationic protein (ECP) in endomyocardium with high serum ECP1999 · 41 citations