Key result
The Harborview Risk Score best predicted 30-day mortality after ruptured abdominal aortic aneurysm repair, with each point increase associated with higher mortality (OR 2.4; 95% CI 1.68-3.56; P<0.001).
Why the study?
Several scores exist to predict 30-day mortality after intervention for ruptured abdominal aortic aneurysm, but their performance had not been compared in an Australasian cohort including nonoperative and indigenous populations.
Does the Harborview Risk Score better predict 30-day mortality compared to ERAS and GAS in patients with ruptured abdominal aortic aneurysm?
Cohort (n=256)
Yes
Does the Harborview Risk Score better predict 30-day mortality compared to ERAS and GAS in patients with ruptured abdominal aortic aneurysm?
Odds Ratio: 2.4 (95% CI 1.68–3.56)
p-value: p=<0.001
The Harborview Risk Score demonstrates superior discriminative ability compared to ERAS and GAS for predicting 30-day mortality in patients undergoing open or endovascular repair for ruptured abdominal aortic aneurysms.
BACKGROUND: Several scores exist to predict 30 day mortality after intervention for a ruptured abdominal aortic aneurysm (rAAA). This multicenter study is the first to compare the performance of three scores in an Australasian cohort, including nonoperative and indigenous populations. METHODS: All patients presenting with an rAAA managed operatively and nonoperatively between 2010 and 2024 to five hospitals in the Midland region of New Zealand were included. Three risk prediction scores were calculated: Harborview Risk Score (HRS), Edinburgh Ruptured Aneurysm Score (ERAS), and Glasgow Aneurysm Score (GAS). The discriminative ability of the scores was calculated using receiver operating characteristics curves. RESULTS: A total of 256 patients were included in this study. The HRS score was a better predictor of 30-day mortality in both operative groups, with an area under the curve (AUC) of 0.83 (P value 0.042 versus all) in the endovascular group and 0.69 (P value 0.086 versus all) in the open repair group. The ERAS and GAS scores had an AUC 0.664 and 0.612, respectively, and thus performed less well at predicting 30-day mortality. There was a 2.4-fold increase in 30-day mortality with each increase in HRS point (odds ratio 2.4, 95% confidence interval 1.68-3.56, P value <0.001). CONCLUSION: Of all the scores, the HRS demonstrated the best discriminative ability to predict 30-day mortality in open and endovascular repairs. The risk prediction scores in conjunction with clinical assessments of patients can be used to assist in the clinical decision-making process for patients presenting with an rAAA.
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Dholakia et al. (2025) conducted a cohort in ruptured abdominal aortic aneurysm (rAAA) (n=256). Harborview Risk Score (HRS) vs. Edinburgh Ruptured Aneurysm Score (ERAS) and Glasgow Aneurysm Score (GAS) was evaluated on 30-day mortality (OR 2.4, 95% CI 1.68-3.56, p=<0.001). The Harborview Risk Score best predicted 30-day mortality after ruptured abdominal aortic aneurysm repair, with each point increase associated with higher mortality (OR 2.4; 95% CI 1.68-3.56; P<0.001).
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