Key result
Emergency PCI was a strong independent favorable factor for in-hospital survival (OR 55.016) in STEMI patients with medium- and high-risk TIMI scores, alongside normal lymphocyte, protein, and sodium levels.
Why the study?
STEMI is a time-sensitive emergency, prompting this study to screen favorable factors for survival in patients with medium- and high-risk TIMI scores.
Do emergency PCI and higher baseline levels of lymphocytes, total protein, albumin, and sodium improve in-hospital survival in STEMI patients with medium- and high-risk TIMI scores?
Cohort (n=433)
No
Do emergency PCI and higher baseline levels of lymphocytes, total protein, albumin, and sodium improve in-hospital survival in STEMI patients with medium- and high-risk TIMI scores?
In STEMI patients with medium- to high-risk TIMI scores, undergoing emergency PCI and having higher baseline levels of lymphocytes, total protein, albumin, and sodium are associated with significantly improved in-hospital survival.
Answers are grounded in this paper and cite their sources.
Higher LYM/TP/ALB/Na and emergency PCI associated with survival in medium/high-risk TIMI STEMI; leaves open prospective validation before risk stratification use.
Objective ST-segment myocardial infarction (STEMI) is a time-sensitive emergency. This study screened the favorable factors for the survival of STEMI patients with medium- and high-risk thrombolysis in myocardial infarction (TIMI) scores. Methods According to the TIMI scores at admission, 433 STEMI patients were retrospectively and consecutively selected and allocated into low-/medium-/high-risk groups, with their general information/blood routine/biochemical indicators/coagulation indicators documented. The factors influencing the in-hospital survival of STEMI patients were analyzed using univariate and multivariate logistic regression analyses. Moreover, the predictive value of favorable factors was analyzed by receiver operating characteristics (ROC) curve, and patients were assigned into high/low level groups based on the cut-off value of these factors, with their in-hospital survival rates compared. Results The in-hospital survival rate of the medium-/high-risk groups was lower than that of the low-risk group. Emergency percutaneous coronary intervention (PCI), lymphocyte (LYM), total protein (TP), albumin (ALB), and sodium (Na) were independent favorable factors for in-hospital survival in the medium-/high-risk groups. Besides, LYM > 1.275 × 10 9 /L, TP > 60.25 g/L, ALB > 34.55 g/L, and Na > 137.9 mmo1/L had auxiliary predictive value for the survival of STEMI patients with medium-/high-risk TIMI scores. Patients with high levels of LYM, TP, ALB, and Na exhibited higher in-hospital survival rates than patients with low levels. Conclusion For STEMI patients with medium- and high-risk TIMI scores, accepting emergency PCI and normal levels of LYM, TP, ALB, and Na were more conducive to in-hospital survival.
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Luo et al. (2023) conducted a cohort in ST-segment elevation myocardial infarction (STEMI) (n=433). Emergency percutaneous coronary intervention (PCI) vs. No emergency PCI was evaluated on In-hospital survival in medium- and high-risk TIMI score groups (OR 55.016, 95% CI 4.868-621.757, p=0.001). Emergency PCI was a strong independent favorable factor for in-hospital survival (OR 55.016) in STEMI patients with medium- and high-risk TIMI scores, alongside normal lymphocyte, protein, and sodium levels.
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