Key result
Early diagnosis of diffuse large B-cell lymphoma with cardiac involvement in a 72-year-old woman prevented cardiac complications from the disease and its treatment.
Why the study?
Antemortem diagnosis of secondary cardiac lymphoma remains suboptimal, worsening prognosis with delayed diagnosis, and data on modified chemotherapy to prevent treatment-related complications are limited.
Case Report (n=1)
Cardiac involvement in lymphoma can be easily missed, and early diagnosis with an individualized treatment approach is crucial to prevent fatal complications.
Case reports underscore diagnostic delays and chemotherapy risks in cardiac lymphoma; leaves open whether modified regimens safely improve outcomes.
The antemortem diagnosis of secondary cardiac involvement by lymphoma remains suboptimal. Prognosis is worse with delayed diagnosis as the tumor burden increases with the multicompartment participation. Chemotherapy may improve survival, but there is a risk of mortality due to treatment-related complications, such as myocardial rupture and fatal arrhythmias. Modified chemotherapy regimens may prevent such complications, but the data are limited. We report the case of a 72-year-old woman diagnosed with diffuse large B-cell lymphoma with cardiac involvement, where early diagnosis prevented cardiac complications from the disease and its treatment as well. The aim of this case report is to highlight the fact that cardiac involvement in lymphoma is frequent and can be easily missed, leading to complications. Treatment requires an individualized approach.
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Prakash et al. (2024) conducted a case report in Diffuse large B-cell lymphoma with cardiac involvement (n=1). Early diagnosis and individualized treatment was evaluated. Early diagnosis of diffuse large B-cell lymphoma with cardiac involvement in a 72-year-old woman prevented cardiac complications from the disease and its treatment.
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