Key result
Seven fatal enterovirus 71 strains isolated in China in 2014 shared 94.2% to 99.8% genomic identity and were all assigned to subgenotype C4a based on phylogenetic analysis.
The study provides whole-genome sequences of seven fatal EV71 strains from southern China, identifying them as subgenotype C4a.
No change to EV71 management; leaves open C4a virulence determinants in fatal cases.
The whole-genome sequences of seven fatal enterovirus 71 (EV71) strains, isolated in southern China, in 2014, were determined. The complete genome sequences of these strains displayed close relationships to native EV71 strains and showed 94.2% to 99.8% identity to each other. All of these strains were assigned to subgenotype C4a based on phylogenetic analysis of the VP1 gene.
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Chen et al. (2016) studied this question. Seven fatal enterovirus 71 strains isolated in China in 2014 shared 94.2% to 99.8% genomic identity and were all assigned to subgenotype C4a based on phylogenetic analysis.
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