Key result
Phylodynamic analysis of coxsackievirus B5 strains in Europe revealed that immune selection pressure drove the emergence of two genogroups with opposed evolutionary pathways and alternating prevalence.
Authors
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Supports enhanced genomic surveillance of coxsackie B5; leaves open whether genogroup alternation alters cardiac complication rates.
Observational
Yes
Henquell et al. (2013) conducted an observational in Coxsackievirus B5 (CVB5). Coxsackievirus B5 genogroups A and B was evaluated on Phylodynamic patterns and evolutionary processes. Phylodynamic analysis of coxsackievirus B5 strains in Europe revealed that immune selection pressure drove the emergence of two genogroups with opposed evolutionary pathways and alternating prevalence.
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