Key result
Type 2 diabetes was associated with a significantly increased LF/HF ratio compared to healthy controls (1.65 vs 0.79, p<0.001), indicating sympathovagal imbalance.
Population
90 subjects aged 30-60 years, comprising 30 patients with type 2 diabetes mellitus, 30 prediabetic subjects…
Design
Case-control
Authors
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May warrant autonomic evaluation in T2D; leaves open prognostic or therapeutic implications.
Cross-Sectional (n=90)
No
Absolute Event Rate: 1.65% vs 0.79%
p-value: p=<0.001
Alterations in sympathovagal balance, indicated by reduced heart rate variability, begin early in the disease process of diabetes, even during the prediabetic stage before significant elevations in HbA1c.
Mishra et al. (2017) conducted a cross-sectional in Type 2 Diabetes Mellitus and Prediabetes (n=90). Type 2 Diabetes Mellitus vs. Healthy controls was evaluated on LF/HF ratio (p=<0.001). Type 2 diabetes was associated with a significantly increased LF/HF ratio compared to healthy controls (1.65 vs 0.79, p<0.001), indicating sympathovagal imbalance.
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