Key result
Nonlinear strain-hardening characteristics and longitudinal pre-stressing heavily influence the radial deformation, maximum strain-energy density, and radial resonance frequencies of human arteries.
Population
Mathematical models of human artery segments representing healthy, atherosclerotic, and aneurysmatic…
Comparison
Simulation of dynamic response to time-dependent… vs Linear arterial models and zero-order nonlinear…
Design
Preclinical
Authors
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Models ignoring nonlinear strain-hardening and prestress risk inaccurate arterial predictions; leaves open clinical translation.
Nonlinear hyperelastic modeling of human arteries reveals that strain-hardening and longitudinal pre-stressing significantly affect radial deformation and resonance frequencies, which may help explain murmurs in stenotic arteries.
Charalambous et al. (2017) studied Arterial dynamics (healthy, atherosclerotic, and aneurysmatic). Strain hardening (hyperelastic models) vs. Linear arterial models was evaluated on Radial deformation and maximum strain-energy density. Nonlinear strain-hardening characteristics and longitudinal pre-stressing heavily influence the radial deformation, maximum strain-energy density, and radial resonance frequencies of human arteries.
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