Why the study?
Does phenprocoumon improve anticoagulation control and stability compared to acenocoumarol in patients requiring oral anticoagulant therapy?
Population
22,178 patients requiring oral anticoagulant therapy managed at six regional anticoagulation clinics in the…
Comparison
Phenprocoumon vs Acenocoumarol
Design
Cohort
Follow-up
3 years
Authors
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Phenprocoumon was associated with modestly higher TTR than acenocoumarol; leaves open whether this improves outcomes in randomized trials.
Does phenprocoumon improve anticoagulation control and stability compared to acenocoumarol in patients requiring oral anticoagulant therapy?
Phenprocoumon provides better anticoagulation control and stability with fewer monitoring visits compared to acenocoumarol.
Gadisseur et al. (2003) studied this question.