Key result
Microvascular heterogeneity significantly impacts oxygen supply and organ function, and physiological control mechanisms involving structural adaptation and flow regulation are essential to mitigate these effects.
Design
Review
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Microvascular heterogeneity may impair oxygen delivery; leaves open targeted mitigation of extrinsic versus intrinsic sources.
Restoration of endothelial function and conducted responses should be considered when addressing tissue hypoxemia and organ failure in clinical settings.
Roy et al. (2022) conducted a review in Microvascular heterogeneity and oxygen transport. Microvascular heterogeneity significantly impacts oxygen supply and organ function, and physiological control mechanisms involving structural adaptation and flow regulation are essential to mitigate these effects.
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