Why the study?
Insulin resistance is correlated with atherosclerosis development, but few studies have investigated its association with asymptomatic intracranial arterial stenosis.
Is insulin resistance or diabetes mellitus associated with asymptomatic intracranial arterial stenosis in adults without prior stroke or TIA?
Population
2007 rural residents in China aged ≥40 years without stroke or transient ischaemic attack
Comparison
Insulin resistance or diabetes mellitus vs absence of these conditions
Design
Cross-sectional study
Authors
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IR associated with aICAS only in rural Chinese men; leaves open whether IR screening identifies stroke risk or warrants intervention.
Is insulin resistance or diabetes mellitus associated with asymptomatic intracranial arterial stenosis in adults without prior stroke or TIA?
Insulin resistance is independently associated with asymptomatic intracranial arterial stenosis in men living in rural China, suggesting a sex-specific metabolic risk factor for cerebrovascular disease.
Wang et al. (2020) studied this question.
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