Why the study?
Does coronary flow velocity reserve (CFR) measured by stress transoesophageal echocardiography predict long-term clinical outcomes in patients undergoing LAD-PCI?
Does coronary flow velocity reserve (CFR) measured by stress transoesophageal echocardiography predict long-term clinical outcomes in patients undergoing LAD-PCI?
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Improvement in coronary flow velocity reserve measured by stress transoesophageal echocardiography after PCI is associated with favorable long-term clinical outcomes.
OBJECTIVES: The aim of the present study was to examine the long-term prognostic value of coronary flow velocity reserve (CFR) evaluated by means of stress transoesophageal echocardiography (STEE) in patients who have undergone percutaneous coronary intervention (PCI). DESIGN: The study comprised 31 patients with significant LAD stenosis who underwent LAD-PCI. In consequence of their clinical signs, 11 subjects required rePCI or coronary artery bypass graft (CABG) operation within six months. The clinical status of the remaining 20 cases improved during the follow-up. STEE examinations were performed before LAD-PCI and after it. RESULTS: The CFR of patients in a stable clinical condition improved during the follow-up, while the CFR of those who required rePCI or CABG remained unchanged. From this patient population, two subjects died during the 5-year follow-up. CONCLUSIONS: Most of the patients who displayed an improved CFR after PCI suffered no major clinical events during the 5-year follow-up; in contrast, in those who a priori had a low CFR and did not show any improvement after PCI, major events did occur during this period.
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Nemes et al. (2005) studied this question.
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