What question did this study set out to answer?

To assess the prevalence, clinical significance, and incremental follow-up costs of incidental extracolonic findings detected during computed tomographic colonography screening.

December 1, 2005The American Journal of Gastroenterology

Computed Tomographic Colonography: Prevalence, Nature, and Clinical Significance of Extracolonic Findings in a Community Screening Program

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Authors

MCMarcus ChinOxford Brookes University RMRichard MendelsonThe University of Western Australia JEJohn T. EdwardsVeterinary Medicines Directorate

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Implication

Prospective screening study reveals incidental extracolonic findings in 27.3% of average-risk adults, indicating modest follow-up costs that target reporting can further reduce.

Key Points

To assess the prevalence, clinical significance, and incremental follow-up costs of incidental extracolonic findings detected during computed tomographic colonography screening.
Prospective screening cohort of 432 asymptomatic adults aged 50–69 years at average risk for colorectal neoplasia.
Subjects underwent low-radiation-dose computed tomographic colonography, with prospective axial image review and follow-up tracking of all clinically relevant extracolonic lesions to tally incremental costs.
Extracolonic lesions totaled 146 across 118 subjects (27.3%), with 32 subjects (7.4%) exhibiting clinically relevant abnormalities and 9 (2.1%) potentially deriving clinical benefit.
The baseline scan cost was $171.12, and clinical follow-up for extracolonic findings generated an additional incremental cost of $24.37 (14.2%) per scan.
Restricting reporting exclusively to the aorta and kidneys reduced the follow-up requirement to 14 subjects (3.2%) and lowered the incremental cost to 4.7% without compromising clinical outcomes.

Cite This Study

Chin et al. (2005) studied this question.

synapsesocial.com/papers/6a71ed8dac440176ef2a6c61 https://doi.org/10.1111/j.1572-0241.2005.00337.x

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Implication

Prospective screening study reveals incidental extracolonic findings in 27.3% of average-risk adults, indicating modest follow-up costs that target reporting can further reduce.

Computed Tomographic Colonography: Prevalence, Nature, and Clinical Significance of Extracolonic Findings in a Community Screening Program

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Implication

Key Points

Cite This Study

Computed Tomographic Colonography: Prevalence, Nature, and Clinical Significance of Extracolonic Findings in a Community Screening Program

Discussion

Member takes

Implication

Key Points

Cite This Study

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