May 1, 1999The Journal of the American Board of Family MedicineOpen Access

Appropriate Roles of Cardiac Troponins in Evaluating Patients With Chest Pain

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Why the study?

Does cardiac troponin testing improve diagnostic accuracy for acute myocardial infarction compared to CK-MB in patients with chest pain?

Population

Patients with suspected myocardial infarction or chest pain

Comparison

Cardiac troponin I and cardiac troponin T testing vs CK-MB (MB isoenzyme of creatine kinase) testing

Design

Review

Authors

MRMegan S. RiceChildren's Medical Research Institute DMDoune MacdonaldThe University of Sydney

Discussion

Member takes

Implication

Supports troponin I for myocardial injury evaluation; leaves open prospective validation before changing practice.

Structured PICO

Does cardiac troponin testing improve diagnostic accuracy for acute myocardial infarction compared to CK-MB in patients with chest pain?

Population

Patients with suspected myocardial infarction or chest pain

Intervention

Cardiac troponin I and cardiac troponin T testing

Comparator

CK-MB (MB isoenzyme of creatine kinase) testing

Outcome

Diagnostic sensitivity and specificity for acute myocardial infarctionsurrogate

Troponin I offers superior specificity to CK-MB without sacrificing sensitivity, making it the preferred biomarker for evaluating suspected acute myocardial infarction.

Cite This Study

Rice et al. (1999) studied this question.

synapsesocial.com/papers/6a71f019a7fbea1e44088bae https://doi.org/10.3122/jabfm.12.3.214

View Full Paper

Ask AI

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Appropriate Roles of Cardiac Troponins in Evaluating Patients With Chest Pain

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Appropriate Roles of Cardiac Troponins in Evaluating Patients With Chest Pain

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider