June 10, 2016BMC Infectious DiseasesOpen Access

Nucleotide variation in Sabin type 3 poliovirus from an Albanian infant with agammaglobulinemia and vaccine associated poliomyelitis

View Full Paper

Ask AI

Bookmark

Population

5-month-old Albanian male infant with X-linked agammaglobulinemia and vaccine-associated paralytic…

Design

Case_report

Follow-up

1 year

Authors

TFThomas FoiadelliUniversity of Pavia SSSalvatore SavastaUniversity of Cagliari ABAndrea BattistoneIstituto Superiore di Sanità

Discussion

Member takes

Implication

Supports caution with OPV in infants at risk for immunodeficiency; leaves open optimal pre-vaccination screening approaches.

Structured PICO

Population

5-month-old Albanian male infant with X-linked agammaglobulinemia and vaccine-associated paralytic poliomyelitis (VAPP) after oral polio vaccine administration (n=1)

Intervention

Intravenous immunoglobulins (IVIG) at 400 mg/kg/dose for 7 days and every three weeks thereafter

Outcome

Viral clearance and neurological improvement

Timely administration of high-dose IVIG in an immunodeficient infant with VAPP led to rapid viral clearance and neurological improvement, highlighting the importance of acute flaccid paralysis surveillance.

Cite This Study

Foiadelli et al. (2016) studied this question.

synapsesocial.com/papers/6a71f2892163a0a01bc5dccb https://doi.org/10.1186/s12879-016-1587-y

View Full Paper

Ask AI

Bookmark

Nucleotide variation in Sabin type 3 poliovirus from an Albanian infant with agammaglobulinemia and vaccine associated poliomyelitis

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Nucleotide variation in Sabin type 3 poliovirus from an Albanian infant with agammaglobulinemia and vaccine associated poliomyelitis

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider