January 1, 1987CirculationOpen Access

Regional and global left ventricular function in infants with anomalous origin of the left coronary artery from the pulmonary trunk: preoperative and postoperative assessment.

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Why the study?

Does surgical restoration of a dual coronary artery system improve left ventricular mechanics in infants with ALCA?

Population

6 infants with anomalous origin of the left coronary artery from the pulmonary trunk, 15 age-matched normal…

Comparison

Surgical restoration of a dual coronary artery… vs Preoperative baseline, age-matched normal…

Design

Cohort

Follow-up

7 to 22 months

Authors

ARAzaria J.J.T. ReinHadassah Medical Center SCS D ColanBrigham and Women's Hospital IPIra A. ParnessCohen Children's Medical Center

Discussion

Member takes

Implication

LV volumes normalize after ALCA repair in infants; supports remodeling observations but leaves open questions for larger prospective studies.

Structured PICO

Does surgical restoration of a dual coronary artery system improve left ventricular mechanics in infants with ALCA?

Population

6 infants (2 to 13 months old) with anomalous origin of the left coronary artery from the pulmonary trunk (ALCA), 15 age-matched normal subjects, and 7 age-matched patients with idiopathic congestive cardiomyopathy.

Intervention

Surgical restoration of a dual coronary artery system

Comparator

Preoperative baseline, age-matched normal subjects, and age-matched patients with idiopathic congestive cardiomyopathy

Outcome

Left ventricular mechanics, including regional wall motion, end-diastolic volume, and myocardial volumesurrogate

Surgical repair of ALCA in infants results in the normalization of left ventricular global hypokinesis and volumes within 7 to 22 months postoperatively.

Cite This Study

Rein et al. (1987) studied this question.

synapsesocial.com/papers/6a71f74a5d37378ac1deef04 https://doi.org/10.1161/01.cir.75.1.115

Topics

Echocardiography

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Implication

LV volumes normalize after ALCA repair in infants; supports remodeling observations but leaves open questions for larger prospective studies.

Regional and global left ventricular function in infants with anomalous origin of the left coronary artery from the pulmonary trunk: preoperative and postoperative assessment.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Topics

Regional and global left ventricular function in infants with anomalous origin of the left coronary artery from the pulmonary trunk: preoperative and postoperative assessment.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Topics

Also Consider