Why the study?
Does quantitative myocardial blush grade predict infarct size early in acute infarction in patients with STEMI and NSTEMI treated with primary angioplasty and stent placement?
Does quantitative myocardial blush grade predict infarct size early in acute infarction in patients with STEMI and NSTEMI treated with primary angioplasty and stent placement?
Quantitative myocardial blush grade may offer an objective assessment of infarct size early in acute myocardial infarction following primary angioplasty.
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May support objective early infarct sizing post-angioplasty; hypothesis-generating and requires prospective validation before practice change.
The widespread use of percutaneous coronary interventions has resulted in a significant improvement of clinical outcomes in patients both with ST-elevation and in non-ST-elevation myocardial infarction (STEMI and NSTEMI). The restoration of epicardial artery blood flow in the revascularized coronary artery however, may not necessarily guarantee preserved microvascular integrity in the downstream myocardium. Because the latter is a principal predictor of clinical outcomes, methods that can provide objective assessment of infarct size early in acute infarction may be of great potential clinical utility.
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Riedle et al. (2009) studied this question.
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