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January 1, 2006Scandinavian Cardiovascular JournalOpen Access

Infarct sizes were smaller (p=0.0017) and ejection fractions higher (p=0.0001) in patients with TMP 2-3 compared to TMP 0-1 at 3-month follow-up.

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Why the study?

Does better TIMI myocardial perfusion (TMP 2-3) predict smaller infarct size and higher ejection fraction in patients with STEMI treated successfully with primary angioplasty?

Population

50 patients with acute STEMI and restoration of normal epicardial flow after primary angioplasty

Comparison

TIMI myocardial perfusion grades 2-3 vs TIMI myocardial perfusion grades 0-1

Design

Cohort

Follow-up

3 months

Authors

PHPavel HoffmannSHSigrun HalvorsenKSKnut-Haakon Stensæth

Discussion

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Overview

TMP 2-3 may aid post-PCI risk stratification in STEMI; leaves open whether perfusion grading should guide therapy.

Structured PICO

Does better TIMI myocardial perfusion (TMP 2-3) predict smaller infarct size and higher ejection fraction in patients with STEMI treated successfully with primary angioplasty?

P
Population
50 patients with acute STEMI and restoration of normal epicardial flow after primary angioplasty
I
Intervention
TIMI myocardial perfusion (TMP) grades 2-3 (Group B)
C
Comparator
TIMI myocardial perfusion (TMP) grades 0-1 (Group A)
O
Outcome
Myocardial perfusion on early MRI (within 5 days) and infarct size and ejection fraction on MRI at 3 monthssurrogate

In STEMI patients with restored epicardial flow after primary angioplasty, better early myocardial perfusion (TMP 2-3) is associated with smaller infarct size and higher ejection fraction at 3 months.

Cite This Study

Hoffmann et al. (2006) studied this question.

synapsesocial.com/papers/6a85215ee3de713998f23e1chttps://doi.org/10.1080/14017430600628144
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