Key result
Impaired myocardial perfusion predicts ~192% higher 1-year mortality in advanced Killip class STEMI patients.
Why the study?
Does impaired myocardial perfusion predict 1-year mortality in patients with STEMI and heart failure undergoing primary angioplasty?
Cohort (n=1,548)
Does impaired myocardial perfusion predict 1-year mortality in patients with STEMI and heart failure undergoing primary angioplasty?
Relative Risk: 2.92 (95% CI 1.37–6.23)
p-value: p=0.005
Impaired myocardial perfusion independently predicts 1-year mortality in STEMI patients presenting with heart failure (Killip class >1) undergoing primary angioplasty.
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May enhance risk stratification in STEMI with advanced Killip class; hypothesis-generating for perfusion-targeted interventions.
Luca et al. (2004) conducted a cohort in ST-segment-elevation myocardial infarction (STEMI) (n=1,548). Impaired myocardial perfusion (myocardial blush) was evaluated on 1-year mortality (RR 2.92, 95% CI 1.37-6.23, p=0.005). Impaired myocardial perfusion was an independent predictor of 1-year mortality (RR 2.92; 95% CI 1.37-6.23; P=0.005) in STEMI patients with advanced Killip class at presentation.
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