Why the study?
Does surgical stress under halothane anesthesia increase plasma catecholamine levels in patients undergoing elective abdominal operations?
Population
8 patients undergoing elective abdominal operations and 11 normal controls
Comparison
Elective abdominal operations under halothane… vs Pre-anesthesia baseline and normal controls
Design
Cohort
Follow-up
2 hours after surgery
Authors
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Catecholamine surges occur despite halothane in abdominal surgery; leaves open effects on perioperative risk in elective cases.
Does surgical stress under halothane anesthesia increase plasma catecholamine levels in patients undergoing elective abdominal operations?
Surgical stress induces significant adrenergic activation, reflected by increased plasma norepinephrine and epinephrine, which correlates with increases in mean arterial pressure and is not blocked by halothane anesthesia.
Halter et al. (1977) studied this question.
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