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May 1, 1988Circulation

Cardiopulmonary adaptation at rest and during exercise 10 years after Mustard atrial repair for transposition of the great arteries.

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Why the study?

Does cardiopulmonary response to exercise differ in asymptomatic adolescents approximately 10 years after Mustard atrial repair compared to normal controls?

Population

17 asymptomatic adolescent patients with no significant postoperative hemodynamic abnormalities, assessed…

Comparison

Upright bicycle ergometry vs 17 age- and sex-matched normal adolescents

Design

Cross-sectional

Authors

NMNorman N. MuseweUniversity of TorontoJRJoseph ReismanCanadian Paediatric SocietyLBLee BensonPediatric Cardiology

Discussion

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Implication

May support exercise testing in asymptomatic post-Mustard adolescents; leaves open prognostic implications.

Structured PICO

Does cardiopulmonary response to exercise differ in asymptomatic adolescents approximately 10 years after Mustard atrial repair compared to normal controls?

P
Population
17 asymptomatic adolescent patients with no significant postoperative hemodynamic abnormalities, assessed 11.5 +/- 1.5 years after Mustard atrial repair for transposition of the great arteries.
I
Intervention
Upright bicycle ergometry (incremental and steady-state exercise testing)
C
Comparator
17 age- and sex-matched normal adolescents
O
Outcome
Cardiopulmonary response to exercise including maximum work capacity, heart rate, blood pressure, oxygen saturation, minute ventilation, and cardiac outputsurrogate

Despite being asymptomatic at rest, patients approximately 10 years post-Mustard repair for transposition of the great arteries exhibit reduced maximum work capacity and chronotropic impairment during exercise.

Cite This Study

Musewe et al. (1988) studied this question.

synapsesocial.com/papers/6a71fd4c75498292b70b44bdhttps://doi.org/10.1161/01.cir.77.5.1055
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