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September 1, 2004Angiology

Evidence of Left Ventricular Dysfunction in Asymptomatic Elderly Patients with Non-insulin-dependent Diabetes Mellitus

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Why the study?

Does type 2 diabetes impair left ventricular function in asymptomatic elderly patients without other cardiovascular diseases?

Population

48 subjects total: 24 asymptomatic elderly patients with type 2 diabetes and no history of hypertension…

Design

Case-control

Authors

HKHaralampos KarvounisAHEPA University HospitalCPChristodoulos PapadopoulosAristotle University of ThessalonikiTZTheodora ZaglavaraInterbalkan Medical Center

Discussion

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Overview

May support echo monitoring for subclinical dysfunction in asymptomatic elderly diabetics; leaves open whether intervention improves outcomes.

Structured PICO

Does type 2 diabetes impair left ventricular function in asymptomatic elderly patients without other cardiovascular diseases?

P
Population
48 subjects total: 24 asymptomatic elderly patients (mean age 67 +/- 2 years) with type 2 diabetes and no history of hypertension, coronary or valvular heart disease, and 24 age- and gender-matched normal subjects.
C
Comparator
24 age- and gender-matched normal subjects
O
Outcome
Left ventricular systolic indices (ejection fraction and fractional shortening), diastolic indices (E wave, A wave, E/A ratio, isovolumic relaxation time, and deceleration time), and myocardial performance index (MPI) evaluated with echocardiographysurrogate

Asymptomatic elderly patients with type 2 diabetes exhibit significant subclinical left ventricular diastolic dysfunction and impaired myocardial performance compared to healthy controls.

Cite This Study

Karvounis et al. (2004) studied this question.

synapsesocial.com/papers/6a71fe716c240de38cdc4818https://doi.org/10.1177/000331970405500511
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Comparison of Two Different Methods for the Evaluation of Left Ventricular Ejection Fraction in Patients with Coronary Artery Disease2002 · 5 citations
  2. 2Doppler Echocardiography for Assessing Left Ventricular Diastolic Function1988 · 121 citations
  3. 3Congestive Heart Failure in the Community1998 · 1,091 citations
  4. 4Echocardiographic determination of left ventricular mass in man. Anatomic validation of the method.1977 · 4,511 citations
  5. 5Diabetes, fibrinogen, and risk of cardiovascular disease: The Framingham experience1990 · 372 citations