Why the study?
Does long-term uncomplicated Type I diabetes mellitus cause left ventricular systolic or diastolic dysfunction at rest compared to healthy controls?
Population
20 patients with insulin-dependent diabetes mellitus, mean age 35 +/- 8 years, mean diabetes duration 17 +/…
Comparison
Long-term Type I Diabetes Mellitus vs 20 age- and sex-matched control subjects
Design
Cross-sectional
Authors
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Does not support resting LV dysfunction in uncomplicated long-term T1DM; leaves open effects of complications or stress.
Does long-term uncomplicated Type I diabetes mellitus cause left ventricular systolic or diastolic dysfunction at rest compared to healthy controls?
Long-term Type 1 diabetes mellitus without concomitant microvascular complications, neuropathy, or ischemic heart disease does not appear to cause resting left ventricular systolic or diastolic dysfunction.
Romanens et al. (1999) studied this question.
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