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January 30, 2016Blood Coagulation & Fibrinolysis

Patients with severe PTS had significantly lower ultrasound-generated GSM (median 24) compared to those with mild-moderate PTS (median 35) or no PTS (median 41) (P = 0.04).

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Why the study?

Is the echogenicity of residual vein thrombosis associated with the severity of postthrombotic syndrome in patients with a history of deep venous thrombosis?

Population

56 patients with a history of deep venous thrombosis in the past 58 months.

Design

Cross-sectional

Authors

BMBruna de Moraes MazettoFOFernanda Andrade OrsiSSSandra Aparecida Ferreira Silveira

Discussion

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Overview

Severe PTS linked to hypoechoic RVT; hypothesis-generating for echogenicity as PTS severity marker.

Structured PICO

Is the echogenicity of residual vein thrombosis associated with the severity of postthrombotic syndrome in patients with a history of deep venous thrombosis?

P
Population
56 patients with a history of deep venous thrombosis in the past 58 months.
I
Intervention
Ultrasound evaluation of residual vein thrombosis (RVT) echogenicity using grayscale median (GSM)
O
Outcome
Association between postthrombotic syndrome (PTS) severity and residual vein thrombosis (RVT) echogenicity (GSM)surrogate

A hypoechoic residual vein thrombosis (GSM < 25) on ultrasound is associated with severe postthrombotic syndrome in patients with a history of deep venous thrombosis.

Cite This Study

Mazetto et al. (2016) studied this question.

synapsesocial.com/papers/6a72046da528af2d65c44898https://doi.org/10.1097/mbc.0000000000000464
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Thrombus Echogenicity and Post-Thrombotic Syndrome Severity After Deep Vein Thrombosis: Insights From Residual Vein Thrombosis Assessment2026 · 1 citations
  2. 2Incidence and predictors of post-thrombotic syndrome in patients with proximal DVT in a real-world setting: findings from the GARFIELD-VTE registry2023 · 17 citations
  3. 3Risk for post-thrombotic syndrome after lower-limb deep vein thrombosis: location of the thrombus or residual thrombi?2021 · 2 citations
  4. 4The Role of Duplex Ultrasound in Diagnosis, Prediction, Treatment and Monitoring of Post‐Thrombotic Syndrome2025
  5. 5Venographic assessment of deep vein thrombosis and risk of developing post‐thrombotic syndrome: a prospective study1993 · 107 citations