Key result
Residual thrombosis identified by venous ultrasonography was predictive of postthrombotic syndrome at 12 months (OR 1.40; 95% CI 0.88-2.21).
Why the study?
The authors aimed to compare the prognostic value of the most proximal extent of thrombus versus residual thrombosis identified by venous ultrasonography during follow-up for the onset of post-thrombotic syndrome after deep venous thrombosis.
Does the presence of residual thrombosis predict postthrombotic syndrome better than the proximal location of the thrombus in patients with a first episode of deep venous thrombosis?
Cohort (n=1,183)
Yes
Does the presence of residual thrombosis predict postthrombotic syndrome better than the proximal location of the thrombus in patients with a first episode of deep venous thrombosis?
Ultrasound finding of residual thrombosis during follow-up is more predictive of postthrombotic syndrome than the initial proximal location of the thrombus after an episode of deep venous thrombosis.
Answers are grounded in this paper and cite their sources.
Suggests follow-up ultrasound may help stratify postthrombotic syndrome risk after deep.
BACKGROUND: Many works aimed to determine factors that influence the onset of postthrombotic syndrome after an acute episode of deep venous thrombosis. We aimed to compare the prognostic value of the most proximal extent of thrombus (proximal and distal DVT) versus the residual thrombosis as identified by venous ultrasonography performed during follow-up. METHOD: We conducted a retrospective study of prospectively collected 1183 consecutive cohort patients in the RIETE registry after a first episode of deep venous thrombosis and assessed for postthrombotic syndrome after 12 months. RESULTS: Multivariate analysis revealed that: residual thrombosis (OR 1.40; 95% CI 0,88-2,21), the presence of cancer (OR 1.38; 95% CI: 0,64-2,97), immobility (OR 1.31; 95% CI 0,70-2,43) and estrogen-containing drugs use (OR 2.08, 95% CI 0,63-6,83), all had a predictive value for the occurrence of PTS. CONCLUSION: Our study results revealed that ultrasound finding of residual thrombosis is more predictive than proximal location of thrombus for postthrombotic syndrome after episode of deep venous thrombosis. Real life data from a large group of patients from the RIETE registry substantiates that.
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Bosevski et al. (2021) conducted a cohort in Deep venous thrombosis (n=1,183). Residual thrombosis vs. Proximal location of thrombus was evaluated on Postthrombotic syndrome (PTS) (OR 1.40, 95% CI 0.88-2.21). Residual thrombosis identified by venous ultrasonography was predictive of postthrombotic syndrome at 12 months (OR 1.40; 95% CI 0.88-2.21).
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