The phospholipid growth factors PA, S1P, and LPA display potent and divergent effects on endothelial cell chemotaxis and barrier stabilization, suggesting they act in tandem to induce neovascularization during hematopoietic restoration.
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These endothelial effects remain preclinical; leaves open tandem phospholipid roles in hematopoietic neovascularization.
English et al. (1999) studied this question.
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