Why the study?
Do newer diagnostic assays (like cTnT-ELISA) improve the detection of minimal myocardial injury compared to common biochemical markers in patients undergoing endomyocardial biopsy?
Population
24 patients (6 female, 18 male, mean age 47 years) undergoing diagnostic endomyocardial biopsy
Comparison
Newer diagnostic assays for detecting myocardial… vs Common biochemical markers
Design
Cohort
Follow-up
2 days
Authors
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May support cTnT-ELISA for sensitive post-biopsy injury detection; hypothesis-generating and should not yet change practice.
Do newer diagnostic assays (like cTnT-ELISA) improve the detection of minimal myocardial injury compared to common biochemical markers in patients undergoing endomyocardial biopsy?
cTnT-ELISA demonstrates superior sensitivity for detecting minimal myocardial injury following endomyocardial biopsy compared to other standard and rapid bedside biomarker assays.
Lang et al. (2000) studied this question.
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