Population
Sewage samples from highly immune populations in Israel and transgenic mice expressing the human receptor…
Design
Other
Follow-up
1998 to 2006
Authors
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Supports enhanced VDPV surveillance; leaves open whether eradication strategies need revision in immune populations.
Vaccine-derived polioviruses can revert to neurovirulence and circulate even in highly immune populations, underscoring the critical role of environmental surveillance in global polio eradication efforts.
Shulman et al. (2006) studied this question.
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