Population
Vaccine-derived poliovirus isolates from an immunocompromised poliomyelitis patient, their contacts, and…
Design
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Signals risk of circulating vaccine-derived poliovirus; leaves open optimal genomic surveillance strategies in eradication programs.
The study demonstrates how oral polio vaccine strains can evolve and establish circulation, highlighting the mechanisms of viral attenuation loss and altered immunological properties.
Cherkasova et al. (2004) studied this question.
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