What question did this study set out to answer?

To examine the physiological mechanisms by which digitalis influences venous pressure and circulation in congestive heart failure.

January 1, 1949HeartOpen Access

The Effect of Digitalis on the Venous Pressure

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Why the study?

Does digitalis affect venous pressure in patients with congestive heart failure?

Design

Review

Authors

PWP. WoodUniversity of Portsmouth JPJany PaulettValve (United States)

Discussion

Member takes

Implication

Historical observations link digitalis to venous pressure reduction; leaves open relevance for contemporary HF trials beyond rate control.

Key Points

To examine the physiological mechanisms by which digitalis influences venous pressure and circulation in congestive heart failure.
Evaluation of clinical hemodynamic responses to digitalis in heart failure patients presenting with auricular fibrillation versus normal cardiac rhythm.
Review of physiological mechanisms in canine models assessing venous pressure changes and hepatic vein constriction.
Digitalis reliably alleviates congestive heart failure, historically associated with ventricular rate slowing in patients with auricular fibrillation.
Experimental findings demonstrate lowered venous pressure via hepatic vein constriction, indicating non-cardiac vascular throttle actions.

Structured PICO

Does digitalis affect venous pressure in patients with congestive heart failure?

Intervention

Digitalis

Outcome

Venous pressuresurrogate

This text reviews historical perspectives on the mechanism of action of digitalis in congestive heart failure, particularly its potential role in lowering venous pressure.

Cite This Study

Wood et al. (1949) studied this question.

synapsesocial.com/papers/6a720b8678a11c550e0bedc2 https://doi.org/10.1136/hrt.11.1.83

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Implication

Historical observations link digitalis to venous pressure reduction; leaves open relevance for contemporary HF trials beyond rate control.

The Effect of Digitalis on the Venous Pressure

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

The Effect of Digitalis on the Venous Pressure

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Also Consider

Also Consider