Metabolic Syndrome and Diabetes, Alone and in Combination, as Predictors of Cardiovascular Disease Mortality Among Men
Why the study?
Does the presence of metabolic syndrome, diabetes, or both increase cardiovascular disease mortality in men?
Population
Men from the Aerobics Center Longitudinal Study, mean age 45.1 +/- 10.2 years, categorized by presence of…
Comparison
Presence of metabolic syndrome only, diabetes… vs Neither diabetes nor metabolic syndrome
Design
Cohort
Follow-up
14.6 +/- 7.0 years
Authors
Discussion
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Member takes
Implication
May warrant closer CVD monitoring in diabetic men; leaves open causal effects and intervention benefits from observational data.
Structured PICO
Does the presence of metabolic syndrome, diabetes, or both increase cardiovascular disease mortality in men?
P
Population
Men from the Aerobics Center Longitudinal Study (ACLS) (n=34,179), mean age 45.1 +/- 10.2 years, categorized by presence of diabetes and/or metabolic syndrome.
I
Intervention
Presence of metabolic syndrome only, diabetes only, or concurrent metabolic syndrome and diabetes
C
Comparator
Neither diabetes nor metabolic syndrome
O
Outcome
Cardiovascular disease (CVD) mortalityhard clinical
Diabetes is associated with a threefold higher risk of CVD mortality in men, and the concurrent presence of metabolic syndrome does not significantly modify this already elevated risk.
Cite This Study
Church et al. (2009) studied this question.