Why the study?
The gold-standard conventional FD-TWA device was commercially discontinued, and normal reference values for a newly available 24-hour AECG-based FD-TWA system were lacking.
Population
312 subjects without heart disease and 30 heart disease patients
Comparison
Subjects without heart disease vs heart disease patients
Design
Cross-sectional observational study
Follow-up
24 hours
Authors
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Provides initial normal values for 24-h FD-TWA via new AECG; leaves open validation for arrhythmic risk stratification.
This study establishes normal reference values for a novel 24-hour ambulatory ECG-based frequency domain T-wave alternans measurement in subjects without structural heart disease.
Hashimoto et al. (2020) studied this question.
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