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February 9, 2018International Journal of Veterinary Science and MedicineOpen Access

Mean serum cTn I showed significant increase (P < 0.001) in FMDV-infected calves (fatal: 2.794 ± 0.502 ng/mL, recovered: 1.196 ± 0.443 ng/mL) compared to healthy controls (0.014 ± 0.002 ng/mL).

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Why the study?

Do cardiac biomarkers (cTn I and CK-MB) diagnose FMD-related myocarditis and predict fatal outcomes in FMDV-infected calves?

Population

Egyptian cattle/calves presenting with mouth lesions and ropy salivation and healthy control cases.

Comparison

Measurement of serum cardiac troponin1 and… vs Healthy control cases

Design

Other

Authors

NSNader M. SobhyYBYasmin BayoumiSMSunil K. Mor

Discussion

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Overview

Identifies FMDV serotypes A and O in Egyptian cattle; leaves open optimal local vaccination and outbreak control strategies.

Structured PICO

Do cardiac biomarkers (cTn I and CK-MB) diagnose FMD-related myocarditis and predict fatal outcomes in FMDV-infected calves?

P
Population
Egyptian cattle/calves presenting with mouth lesions and ropy salivation (FMDV-infected) and healthy control cases.
I
Intervention
Measurement of serum cardiac troponin1 (cTn I) and creatinine kinase myocardial band (CK-MB)
C
Comparator
Healthy control cases
O
Outcome
Diagnosis of FMD-associated myocarditis and prognostic significance for fatal casessurrogate

Serum cTn-I successfully diagnoses FMD-associated myocarditis in calves but is not prognostic for fatal cases.

Cite This Study

Sobhy et al. (2018) studied this question.

synapsesocial.com/papers/6a720eb0f44fa9f079dfaa92https://doi.org/10.1016/j.ijvsm.2018.02.001
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