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June 1, 2018Zagazig Veterinary Journal/Zagazig Veterinary Journal (Online)Open Access

FMDV infection in cattle significantly decreased serum total proteins and calcium, and increased cardiac biomarkers (cTnI, CK-MB), indicating myocardial cell damage.

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Population

45 native breed Egyptian female non-pregnant cattle, including 30 infected with Foot and Mouth Disease Virus…

Comparison

Foot and Mouth Disease Virus (FMDV) infection vs Apparently healthy uninfected cattle

Design

Preclinical

Key result

FMDV infection in cattle significantly decreased serum total proteins and calcium, and increased cardiac biomarkers (cTnI, CK-MB), indicating myocardial cell damage.

Authors

MHMohamed HashemSEShefaa A.M. El-MandrawyIAIman Araby

Discussion

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Overview

Suggests cardiac monitoring in FMDV cattle outbreaks; hypothesis-generating for cross-species viral cardiotoxicity.

Study Design

Type

Case-Control (n=45)

Multicenter

Yes

Structured PICO

P
Population
45 native breed Egyptian female non-pregnant cattle aged 1-5 years, comprising 30 FMDV-infected animals and 15 healthy controls.
E
Exposure
Foot and Mouth Disease Virus (FMDV) infection
C
Comparator
Apparently healthy uninfected cattle
O
Outcome
Hematological parameters, biochemical aspects, and cardiac biomarkers (cTnI, CK-MB)surrogate

FMDV infection in cattle is associated with significant myocardial cell damage as evidenced by elevated cTnI and CK-MB levels.

Cite This Study

Hashem et al. (2018) conducted a case-control in Foot and Mouth Disease Virus (FMDV) (n=45). Foot and Mouth Disease Virus (FMDV) infection vs. Apparently healthy cattle was evaluated on Hematological parameters, biochemical aspects, and cardiac biomarkers. FMDV infection in cattle significantly decreased serum total proteins and calcium, and increased cardiac biomarkers (cTnI, CK-MB), indicating myocardial cell damage.

synapsesocial.com/papers/6a85752d02a1bc3ea31e5d1bhttps://doi.org/10.21608/zvjz.2018.14382
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Outbreaks of foot and mouth disease in Egypt: Molecular epidemiology, evolution and cardiac biomarkers prognostic significance2018 · 47 citations
  2. 2Molecular Epidemiology of Foot and Mouth Disease Virus during 2014 with References to Biochemical Changes in Egyptian Buffaloes2016
  3. 3Advanced Virological And Clinicopathological Studies On Cattle Suffering From Foot And Mouth Disease Virus2017 · 5 citations
  4. 4Clinical Study on Egyptian Cattle Affected With Recent Isolate of Foot and Mouth Disease Virus SAT2/20122014 · 6 citations
  5. 5Pathological and Molecular Investigations on Foot and Mouth Virus Outbreaks Among Cattle Herds in Dakahlia Governorate, Egypt2016 · 6 citations