Why the study?
Does natural infection with FMDV serotype SAT 2 alter hemato-biochemical and cardiac markers in adult buffaloes and calves?
Population
60 Egyptian buffaloes from Sharkia Province, Egypt, comprising 40 adult buffaloes and 20 suckling calves.
Comparison
Natural infection with Foot and Mouth Disease… vs Clinically apparent healthy adult buffaloes and…
Design
Preclinical
Key result
Natural infection with Foot and Mouth Disease Virus serotype SAT 2 in buffalo calves resulted in severe myocardial injury, evidenced by a significant increase in cardiac troponin I (1.78 vs 0.08 ng/ml) and 100% mortality.
Authors
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Severe myocardial injury in FMDV SAT 2-infected buffalo calves warrants targeted cardiac monitoring in outbreaks; leaves open translation to adults or other species.
Cross-Sectional (n=60)
Does natural infection with FMDV serotype SAT 2 alter hemato-biochemical and cardiac markers in adult buffaloes and calves?
Absolute Event Rate: 1.78% vs 0.08%
p-value: p=≤0.01
Natural infection with FMDV serotype SAT 2 causes severe myocardial injury and 100% mortality in buffalo calves, evidenced by significantly elevated cardiac markers (cTnI, LDH, CK-MB) and histopathological changes.
Mahmoud et al. (2016) conducted a cross-sectional in Foot and Mouth Disease (FMD) (n=60). Foot and Mouth Disease Virus (FMDV) serotype SAT 2 infection vs. Clinically healthy buffaloes and calves was evaluated on Cardiac troponin I (cTnI) concentration in buffalo calves (ng/ml) (p=≤0.01). Natural infection with Foot and Mouth Disease Virus serotype SAT 2 in buffalo calves resulted in severe myocardial injury, evidenced by a significant increase in cardiac troponin I (1.78 vs 0.08 ng/ml) and 100% mortality.
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