Key result
Natural infection with foot and mouth disease in buffaloes was associated with lymphocytic leukocytosis, metabolic acidosis, and significant increases in AST (P<0.01) and globulins (P<0.05).
Population
25 buffaloes, aged 1-5 years (15 naturally infected with foot and mouth disease, 10 healthy controls)
Comparison
Natural infection with foot and mouth disease vs Healthy controls
Design
Preclinical
Authors
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May signal cardiac involvement in FMD; hypothesis-generating for myocarditis and requires prospective validation before clinical extrapolation.
Case-Control (n=25)
Foot and mouth disease in buffaloes is associated with significant metabolic disturbances, including metabolic acidosis and elevated AST, as well as interstitial myocarditis.
El‐Amir et al. (2014) conducted a case-control in Foot and mouth disease (FMD) (n=25). Foot and mouth disease (FMD) infection vs. Healthy controls was evaluated on Metabolic profile and pathological findings. Natural infection with foot and mouth disease in buffaloes was associated with lymphocytic leukocytosis, metabolic acidosis, and significant increases in AST (P<0.01) and globulins (P<0.05).
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