Why the study?
Thyroid angiosarcoma is a rare, aggressive vascular tumor mainly described in the Alps that can evolve in non-endemic regions.
Thyroid angiosarcoma, though rare and typically found in Alpine regions, can occur in non-endemic areas and requires prompt surgical excision and multidisciplinary management.
Thyroid angiosarcoma case in elderly adds morphological detail; leaves open need for larger series on management.
Thyroid angiosarcoma (AS) is a specific type of vascular tumor that arises from the endothelial cells, being highly aggressive, with increased recurrence rates and metastasis. It is characterized by positive endothelial markers and co-positive markers for cytokeratins and epithelial membrane antigen. We are describing the case of a 76-year-old patient who presented to the hospital for dyspnea and asthenia. The clinical and paraclinical investigations confirmed the presence of a right large thyroid nodule, which turned out positive at immunostaining for AS. Even if thyroid AS is a rare type of tumor, mainly described in the Alps, one has to take into account that it can evolve in any other regions and should be considered as a differential diagnosis.
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Tulin et al. (2020) studied this question.
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