Why the study?
Doxorubicin is an effective anti-cancer anthracycline, but acute and chronic cardiotoxicity limits its clinical use.
Does quercetin prevent doxorubicin-induced cardiotoxicity and weight loss in a healthy rat model?
Does quercetin prevent doxorubicin-induced cardiotoxicity and weight loss in a healthy rat model?
In a rat model, pretreatment with quercetin protected against doxorubicin-induced cardiotoxicity and weight loss, suggesting potential as a cardioprotective adjunct in anthracycline chemotherapy.
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Quercetin mitigated doxorubicin cardiotoxicity in rats; leaves open clinical translation.
Dulf et al. (2024) studied this question.
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