Why the study?
Do elevated osteopontin plasma levels predict death in patients with chronic heart failure?
Population
420 patients with chronic heart failure due to significantly impaired left ventricular systolic function
Comparison
Osteopontin plasma level measurement vs Healthy control subjects and lower osteopontin…
Design
Cohort
Follow-up
median 43 months
Authors
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May refine risk stratification in chronic HF; observational data leave open incremental value over standard markers.
Do elevated osteopontin plasma levels predict death in patients with chronic heart failure?
Osteopontin is a novel, independent prognostic biomarker for predicting death in patients with chronic heart failure.
Rosenberg et al. (2008) studied this question.
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