Why the study?
Is non-invasive, ultrasound-derived wave intensity analysis at the common carotid artery reproducible at rest and during exercise in healthy young humans?
Is non-invasive, ultrasound-derived wave intensity analysis at the common carotid artery reproducible at rest and during exercise in healthy young humans?
Non-invasive ultrasound-derived wave intensity analysis at the common carotid artery is a reliable physiological measure both at rest and during mild exercise.
Supports research use of carotid WI in healthy subjects; leaves open clinical validation in patients.
The aim of this study was to assess the reproducibility of non-invasive, ultrasound-derived wave intensity (WI) in humans at the common carotid artery. Common carotid artery diameter and blood velocity of 12 healthy young participants were recorded at rest and during mild cycling, to assess peak diameter, change in diameter, peak velocity, change in velocity, time derivatives, non-invasive wave speed and WI. Diameter, velocity and WI parameters were fairly reproducible. Diameter variables exhibited higher reproducibility than corresponding velocity variables (intra-class correlation coefficient [ICC] = 0.79 vs. 0.73) and lower dispersion (coefficient of variation [CV] = 5% vs. 9%). Wave speed had fair reproducibility (ICC = 0.6, CV = 16%). WI energy variables exhibited higher reproducibility than corresponding peaks (ICC = 0.78 vs. 0.74) and lower dispersion (CV = 16% vs. 18%). The majority of variables had higher ICCs and lower CVs during exercise. We conclude that non-invasive WI analysis is reliable both at rest and during exercise.
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Pomella et al. (2017) studied this question.
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