Why the study?
Although the effect of antihypertensive agents on sepsis has been studied, evidence for a survival benefit remained limited.
Does prior use of ACEi or ARB reduce mortality in hypertensive patients who develop sepsis compared to other antihypertensive drugs?
Does prior use of ACEi or ARB reduce mortality in hypertensive patients who develop sepsis compared to other antihypertensive drugs?
Prior use of ACEi or ARB in hypertensive patients is associated with lower 90-day mortality when they develop sepsis compared to other antihypertensive agents.
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Prior ACEI/ARB use was associated with lower sepsis mortality; leaves open causality and whether to alter prescribing.
Kim et al. (2019) studied this question.
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