Why the study?
Does chlorothiazide alter forearm vascular responses to norepinephrine in normal human subjects?
Does chlorothiazide alter forearm vascular responses to norepinephrine in normal human subjects?
Chlorothiazide decreases the responsiveness of forearm vessels to the vasoconstrictor effect of norepinephrine, providing insight into its vascular mechanisms.
No takes yet. Share an insight, caveat, or question.
Chlorothiazide may blunt forearm vasoconstriction to norepinephrine; hypothesis-generating for thiazide vascular effects, needs confirmation.
Feisal et al. (1961) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: