Why the study?
Does diurnal blood pressure variation differ in patients with chronic renal disease compared to matched controls without renal disease?
Does diurnal blood pressure variation differ in patients with chronic renal disease compared to matched controls without renal disease?
Patients with chronic renal disease exhibit blunted nocturnal blood pressure reduction, suggesting that 24-hour ambulatory monitoring may be necessary to appropriately adapt antihypertensive treatment in this population.
Answers are grounded in this paper and cite their sources.
Blunted nocturnal dipping in renal disease may support ambulatory BP monitoring; leaves open effects on outcomes or treatment response.
Diurnal blood pressure variation was studied by ambulatory 24-hour monitoring in patients with advanced chronic renal failure (n = 20), on chronic hemodialysis (n = 20), after renal transplantation (n = 21) and in matched control groups without renal disease. Nocturnal blood pressure reductions were significantly blunted in all patient groups as compared with the respective control groups. In almost none of the 61 controls did the mean values during nighttime (8 p.m.-8 a.m.) exceed the mean day time values (8 a.m.-8 p.m.). In 10 of the 61 renal patients blood pressure was higher during the night. In patients with chronic renal disease nocturnal blood pressure elevation may be diagnosed by ambulatory 24-hour monitoring. This may require adaptation of antihypertensive treatment.
No takes yet. Share an insight, caveat, or question.
Baumgart et al. (2008) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: