Why the study?
Small unrepaired atrial septal defects are considered benign, but recent studies revealed increased long-term mortality and morbidity whose nature is not fully understood.
Do adults with small, unrepaired atrial septal defects have reduced cardiac index during exercise compared to healthy controls?
Do adults with small, unrepaired atrial septal defects have reduced cardiac index during exercise compared to healthy controls?
Adults with small, unrepaired or spontaneously closed atrial septal defects exhibit significantly reduced exercise capacity and cardiac index compared to healthy peers, challenging the notion that these are entirely benign lesions.
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Small ASDs show reduced exercise cardiac index; challenges benign assumption but leaves open management changes pending trials.
Maagaard et al. (2022) studied this question.
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