Why the study?
Does Xinji'erkang improve cardiac remodeling and function in a mouse model of myocardial infarction?
Population
40 male KM mice, aged 8 weeks, weighing 28-30 g, subjected to myocardial infarction via left anterior…
Comparison
Xinji'erkang aqueous extract 7.5 g/kg/day via… vs Model group, Sham group, and active comparator…
Design
Preclinical, randomly assigned into four groups
Follow-up
4 weeks
Authors
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Hypothesis-generating in MI mouse models; leaves open human translation pending clinical trials.
Does Xinji'erkang improve cardiac remodeling and function in a mouse model of myocardial infarction?
Xinji'erkang exerts cardioprotective effects against myocardial infarction-induced remodeling in mice, potentially through improving endothelial dysfunction and reducing oxidative stress and inflammation.
Hu et al. (2017) studied this question.
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