March 1, 1996Cardiovascular ResearchOpen Access

Chaos-related deterministic regulation of heart rate variability in time- and frequency domains: effects of autonomic blockade and exercise

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Why the study?

Does autonomic blockade or exercise alter the non-linear complexity and chaotic behavior of heart rate variability in healthy individuals?

Structured PICO

Does autonomic blockade or exercise alter the non-linear complexity and chaotic behavior of heart rate variability in healthy individuals?

Population

10 healthy individuals (5 men, mean age 44 years)

Intervention

Intravenous injections of propranolol (0.15 mg/kg) followed by atropine (0.03 mg/kg); and on a separate occasion, exercise on a bicycle ergometer at 40% and 70% of maximal working capacity

Comparator

Baseline (at rest)

Outcome

Heart rate variability assessed by dominant Lyapunov exponent, coefficient of variation of heart rate, power spectral analysis of high- and low-frequency bands, 1/f-slope, and time domain analysissurrogate

Heart rate variability exhibits low-dimensional chaos-like determinism that is modulated, but not eliminated, by autonomic blockade or exercise.

Discussion

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Implication

Chaos-like HRV dynamics persist after autonomic blockade or exercise; hypothesis-generating and should not yet change practice.

Cite This Study

Hagerman et al. (1996) studied this question.

synapsesocial.com/papers/6a722c782163a0a01bc5f9dc https://doi.org/10.1016/s0008-6363(95)00084-4

View Full Paper

Ask AI

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Chaos-related deterministic regulation of heart rate variability in time- and frequency domains: effects of autonomic blockade and exercise

Structured PICO

Discussion

Implication

Cite This Study

Chaos-related deterministic regulation of heart rate variability in time- and frequency domains: effects of autonomic blockade and exercise

Structured PICO

Discussion

Implication

Cite This Study

Also Consider

Also Consider