What question did this study set out to answer?

To analyze the progression of coronary artery occlusion after vein bypass surgery in patients.

June 1, 1973CirculationOpen Access

Occlusion of Coronary Arteries after Vein Bypass

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Why the study?

Does aortocoronary-saphenous vein graft surgery accelerate the progression of proximal coronary artery stenosis to complete occlusion compared to nongrafted arteries?

Population

100 patients with coronary artery stenosis undergoing aortocoronary-saphenous vein graft surgery

Comparison

Aortocoronary-saphenous vein graft surgery vs Nongrafted arteries

Design

Cohort

Authors

MMM.R. MalinowUnion College EKE. Louise KremkauOregon Health & Science University FKFrank E. KlosterOregon National Primate Research Center

Discussion

Member takes

Implication

Placement of a saphenous vein bypass graft accelerates the progression of native proximal coronary artery stenosis to complete occlusion, likely due to hemodynamic factors.

Key Points

To analyze the progression of coronary artery occlusion after vein bypass surgery in patients.
Radiographic visualization of coronary arteries in 100 patients
Comparison of occlusions in grafted vs. nongrafted arteries
Focus on stenosis severity in analysis
Nearly 50% of patients with grafted arteries experienced complete occlusion.
Higher incidence of occlusion in severely stenotic grafted arteries than moderately stenotic ones.
Grafted arteries showed occlusion more frequently than those without grafts.

Structured PICO

Does aortocoronary-saphenous vein graft surgery accelerate the progression of proximal coronary artery stenosis to complete occlusion compared to nongrafted arteries?

Population

100 patients with coronary artery stenosis undergoing aortocoronary-saphenous vein graft surgery

Intervention

Aortocoronary-saphenous vein graft surgery

Comparator

Nongrafted arteries (natural course of the disease)

Outcome

Progression of proximal coronary artery stenosis to complete occlusionsurrogate

Placement of a saphenous vein bypass graft accelerates the progression of native proximal coronary artery stenosis to complete occlusion, likely due to hemodynamic factors.

Cite This Study

Malinow et al. (1973) studied this question.

synapsesocial.com/papers/6a7230e2a528af2d65c45762 https://doi.org/10.1161/01.cir.47.6.1211

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Implication

Placement of a saphenous vein bypass graft accelerates the progression of native proximal coronary artery stenosis to complete occlusion, likely due to hemodynamic factors.

Occlusion of Coronary Arteries after Vein Bypass

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Occlusion of Coronary Arteries after Vein Bypass

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

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