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In this investigation, the relationship between rate of appearance of visible colonies of bacteria on cleaned tooth surfaces and the relative concentrations of the specific salivary factor inducing aggregation of Streptococcus mutans, sero-type c strains, was studied. Test subjects were carefully selected in order to minimize the influence of other plaque-provoking factors. In resting, whole saliva, high concentration of the factor was related to a low rate of plaque formation, but in stimulated, whole saliva there was no significant correlation between the concentration of the factor and the rate of plaque formation.
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Magnusson et al. (2009) studied this question.
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